NCT00975559

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 190 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to measure how different people respond to mental stress. The investigators will measure if there are differences in cardiovascular responses to mental stress among different groups of subjects. In one part of the study the investigators will compare the cardiovascular responses to mental stress between healthy women and healthy men. In another part of the study, the investigators will compare the cardiovascular responses to mental stress between women with apical ballooning syndrome and healthy post-menopausal women. The investigators hypothesize that healthy men will have an increased vascular response to and decreased endothelial function in response to to mental stress, compared to health women. Furthermore, the investigators hypothesize that women with apical ballooning syndrome will have an increased vascular response to and decreased endothelial function in response to mental stress.

Conditions

• Coronary Endothelial Dysfunction
• Apical Ballooning Syndrome
• Myocardial Infarction

Timeline

• Start date: 2003-09-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2009-09-11
• Last updated: 2012-04-26

Locations

1 site across 1 country: United States