NCT00974961

Levobupivacaine on Heart Rate Variability (HRV) in Spinal Anesthesia

Comparison of the Effects of Levobupivacaine and Bupivacaine on Heart Rate Variability in Spinal Anesthesia

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare if the effect of levobupivacaine on autonomic nervous system smaller than that of bupivacaine.

Detailed description

Obtain the heart rate variability (in means and standard deviation, including the high frequency, low frequency and its ratio) data of before and after spinal anesthesia with ECG (and Heart Rate Variability Analyzer) in 2 groups. Meanwhile, record the blood pressure on each subject.

Conditions

• Spinal Anesthesia

Interventions

Type	Name	Description
DRUG	bupivacaine, levobupivacaine	intrathecal injection 15\~20mg(for Levobupivacaine) or 10\~15mg(for Bupivacaine) once

Timeline

• Start date: 2009-09-01
• Primary completion: 2009-12-01
• Completion: 2010-07-01
• First posted: 2009-09-11
• Last updated: 2010-03-18

Locations

1 site across 1 country: Taiwan