NCT00973414

Fluid Management for Cesarean Section III

Fluid Management for Cesarean Section Undergoing Combined Spinal Epidural Anesthesia (CSEA)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 850 (actual)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: Female
• Age: 21 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Regional anesthesia, including epidural, spinal and combined epidural spinal anesthesia (CSEA), is a pivotal part in modern anesthesiology. Previously, the investigators found that epidural and spinal anesthesia during cesarean section possesses different responsiveness to fluid (including crystalloid and colloid) management given prior or posterior to anesthesia. Although CSEA is also widely used as an alternative of single epidural or spinal anesthesia for its combined effect of fast onset of anesthesia of spinal anesthesia and the property of duration of epidural catheterization, the fluid resuscitation during CSEA is still unknown. The investigators hypothesized that fluid management during CSEA would produce different effect on hemodynamics in cesarean section compared with epidural and spinal anesthesia.

Conditions

• Cesarean Section

Interventions

Type	Name	Description
DRUG	Ringer's Lactate	Ringer's Lactate 8 ml/kg was given intravenously before or after CSEA in cesarean section
DRUG	Six percent hydroxyethyl starch	Hydroxyethyl starch (6%) was given before or after CSEA in cesarean section

Timeline

• Start date: 2009-03-01
• Primary completion: 2009-09-01
• Completion: 2009-09-01
• First posted: 2009-09-09
• Last updated: 2009-09-09

Locations

1 site across 1 country: China