Trials / Unknown
UnknownNCT00969241
The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- The Baruch Padeh Medical Center, Poriya · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.
Detailed description
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection. Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.
Conditions
Timeline
- Start date
- 2009-07-01
- Primary completion
- 2010-12-01
- First posted
- 2009-09-01
- Last updated
- 2010-12-23
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT00969241. Inclusion in this directory is not an endorsement.