NCT00968045

Fibrinogen and Bleeding After Cardiac Surgery

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Sahlgrenska University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The study hypothesis is that prophylactic fibrinogen infusion reduces postoperative bleeding and transfusion requirements after coronary artery bypass surgery (CABG) in patients with endogenous fibrinogen levels in the lower normal range. 60 patients will be included in a prospective, randomized double-blind placebo-controlled single center study.

Conditions

• Complications
• Bleeding
• Coronary Artery Disease

Interventions

Type	Name	Description
DRUG	Fibrinogen	Fibrinogen 2 gr in 100 ml sterile water. The infusion is given during 15 minutes

Timeline

• Start date: 2009-04-01
• Primary completion: 2012-02-01
• Completion: 2015-05-01
• First posted: 2009-08-28
• Last updated: 2015-05-20

Locations

1 site across 1 country: Sweden