Clinical Trials Directory

Trials / Completed

CompletedNCT00965107

Onset Time of Thiopental Versus Propofol in the Elderly

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
78 (estimated)
Sponsor
Rigshospitalet, Denmark · Academic / Other
Sex
All
Age
60 Years
Healthy volunteers
Not accepted

Summary

This study is aimed at increasing the safety of the use of anaesthesia in an elderly population (\> 60 years). Patients with decreased physiological reserve, including all elderly patients, have an increased risk of getting an erroneous induction bolus. This project will investigate how fast elderly patients (\> 60 years) fall asleep during bolus induction of anaesthesia with two of the most used hypnotics, thiopental and propofol, evaluated with BIS-monitoring and clinical signs of anaesthetic depth. The hemodynamic response will also be evaluated.

Conditions

Interventions

TypeNameDescription
DRUGThiopentalThiopental given as a bolus dose of 2,5 mg/kg.
DRUGPropofolPropofol given as a bolus dose of 1 mg/kg.

Timeline

Start date
2009-09-01
Primary completion
2010-03-01
Completion
2010-03-01
First posted
2009-08-25
Last updated
2010-03-09

Locations

2 sites across 1 country: Denmark

Source: ClinicalTrials.gov record NCT00965107. Inclusion in this directory is not an endorsement.