NCT00964275

Standard Diagnostic Procedures With or Without Fludeoxyglucose F 18 Positron Emission Tomography in Finding Cancer in Patients With a Blood Clot in a Vein

Study of Positron Emission Tomography With 18-fluorodeoxyglucose in Detecting Cancer in Patients With Idiopathic Venous Thromboembolism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (actual)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

RATIONALE: Diagnostic procedures, such as fludeoxyglucose F 18 positron emission tomography, may help find and diagnose cancer. It is not yet known whether standard diagnostic procedures are more effective when given with or without fludeoxyglucose F 18 positron emission tomography in finding cancer. PURPOSE: This randomized clinical trial is studying fludeoxyglucose F 18 positron emission tomography given together with standard diagnostic procedures to see how well it works compared with standard diagnostic procedures alone in finding cancer in patients with a blood clot in a vein.

Detailed description

OBJECTIVES: Primary * Demonstrate the efficacy, in terms of increased numbers of cancer diagnoses, of PET-CT with 18-FDG in patients with idiopathic venous thromboembolism. Secondary * Assess the risk of cancer detected at 1 year. * Assess whether PET allows earlier detection of cancer. * Evaluate survival. OUTLINE: This is a multicenter study. All patients undergo standard (clinical and biological) diagnostic tests for cancer. Patients are randomized to 1 of 2 diagnostic arms. * Arm I: Patients undergo diagnostic fludeoxyglucose F 18 PET in addition to standard methods. * Arm II: Patients only undergo standard diagnostic methods. Patients are followed up for 2 years.

Conditions

• Thromboembolism
• Unspecified Adult Solid Tumor, Protocol Specific

Interventions

Type	Name	Description
PROCEDURE	diagnostic procedure	Standard diagnostic procedures followed
RADIATION	fludeoxyglucose F 18	PET with flueoxyglucose F 18

Timeline

• Start date: 2009-03-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2009-08-24
• Last updated: 2014-12-08

Locations

1 site across 1 country: France