NCT00962949

The Renin-Aldosterone Axis in Postural Tachycardia Syndrome

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Vanderbilt University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the role of the renin-angiotensin-aldosterone in the pathophysiology of postural tachycardia syndrome, and to provide an insight about the disease process in this disorder.

Conditions

• Postural Orthostatic Tachycardia Syndrome (POTS)

Interventions

Type	Name	Description
DRUG	Angiotensin II	Angiotensin II infusion for 1 hour

Timeline

• Start date: 2009-04-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2009-08-20
• Last updated: 2025-09-16
• Results posted: 2018-08-17

Locations

1 site across 1 country: United States