Clinical Trials Directory

Trials / Completed

CompletedNCT00957177

Analgetic Effect of Preoperative Pregabalin in Patients Undergoing Nephrectomy

Effect of Preoperative Pregabalin Administration on the Postoperative Opioid Consumption in Patients Undergoing Nephrectomy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
Medical University of Graz · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Accepted

Summary

Pregabalin 300mg or placebo are administered 1 hour preoperatively in patients undergoing elective nephrectomy. Postoperatively, patients receive a patient controlled analgesia device for self delivering opioids. Morphine consumption in the first 48 hours is documented. Hyperalgesia is measured by von-Frey-Filaments.

Conditions

Interventions

TypeNameDescription
DRUGPregabalin300mg pregabalin orally 1 hour before operation
DRUGPlaceboPlacebo

Timeline

Start date
2009-04-01
Primary completion
2010-12-01
Completion
2010-12-01
First posted
2009-08-12
Last updated
2011-05-27

Locations

1 site across 1 country: Austria

Source: ClinicalTrials.gov record NCT00957177. Inclusion in this directory is not an endorsement.