NCT00955071

Effects of Exercise on Abdominal Obesity and Risk Factors for Cardiovascular Disease

Dose-response Effects of Exercise on Abdominal Obesity and Risk Factors for CVD in Men and Women.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 320 (estimated)
• Sponsor: Queen's University · Academic / Other
• Sex: All
• Age: 35 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The investigators will randomize abdominally obese men and women at increased health risk to one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume, low intensity exercise (LVLI), 3) High volume, low intensity exercise (HVLI), 4) Low volume, high intensity exercise (LVHI). The primary aim of the trial is to determine the effects of varying exercise dose (energy expenditure, kcal) or intensity (relative to VO2max (cardiorespiratory fitness)) on waist circumference and glucose tolerance. The investigators will test the following hypotheses: 1) That the reduction in waist circumference and improvement in glucose tolerance in response to all treatments will be greater than controls. 2) That reduction in waist circumference and improvement in glucose tolerance in HVLI and LVHI will be greater than LVLI. 3) That hypotheses 1 and 2 are true independent of gender.

Conditions

• Obesity
• Metabolic Syndrome
• Cardiovascular Disease

Interventions

Type	Name	Description
OTHER	Exercise: LVLI	low volume, low intensity
OTHER	Exercise: HVLI	high volume, low intensity
OTHER	Exercise: LVHI	low volume, high intensity

Timeline

• Start date: 2009-09-01
• Primary completion: 2013-05-01
• Completion: 2013-05-01
• First posted: 2009-08-07
• Last updated: 2013-08-02

Locations

1 site across 1 country: Canada