NCT00953017

A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy

A Randomized, Blinded Trial Comparing Miralax With Amitiza Pretreatment Versus Miralax With Dulcolax Pretreatment Versus Miralax Alone Without Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 425 (actual)
• Sponsor: Brooke Army Medical Center · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Miralax (PEG 3350) has been shown to be a safe and uncomplicated bowel preparation prior to colonoscopy in pediatric populations. This study seeks to confirm the efficacy of this bowel cleansing regimen in adults and to determine the benefit of adding a pretreatment medication to this bowel preparation. The tolerability of Miralax will hopefully improve patient satisfaction with colonoscopy and decrease their reluctance to be screened because of the uncomfortable taste and side effects of bowel preparation regimens.

Conditions

• Colonoscopy

Interventions

Type	Name	Description
DRUG	Miralax (PEG 3350)	Miralax 255gm bottle
DRUG	Amitiza (Lubiprostone)	Amitiza 24mcg gelcap
DRUG	Dulcolax (Bisacodyl)	Bisacodyl 5mg tab x2
DRUG	Golytely (polyethylene glycol)	Golytely 1 gallon

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2009-08-06
• Last updated: 2012-11-30
• Results posted: 2012-11-30

Locations

1 site across 1 country: United States