NCT00951756

Controlled Feeding Experiment

Controlled Feeding Experiment of High and Low Fat Diet and Stool Microbiome Controlled Feeding Experiment of High and Low Fat Diet and Stool Microbiome Composition

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: James Lewis · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the effect of dietary fat, in standard formulation, on the composition of the human microbiome in a prospective study of normal volunteers. Participants will be randomly assigned to either a high fat or low fat diet for 10 days. The gut microbiome will be phylotyped in fecal samples as well as in bacteria adherent to the colonic mucosa prior to, and during the course of the dietary interventions.

Conditions

• Effect of Diet on Microbiome Composition

Interventions

Type	Name	Description
OTHER	High fat diet	High fat diet and low fat diet are composed of the same food, but the portion sizes are varied.

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-01-01
• Completion: 2011-08-01
• First posted: 2009-08-04
• Last updated: 2013-06-25

Locations

1 site across 1 country: United States