NCT00948792

Study of the Effect of Differing Platelet Transfusion Times in Neonates

The Effect of Variable Platelet Transfusion Durations on Platelet Count in Thrombocytopenic Newborns

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

To evaluate changes in platelet counts and hemodynamics between "rapid" and "long" platelet infusion groups.

Detailed description

1. It is our hypothesis that the change in post-transfusion platelet counts of babies who receive platelets over 30 minutes (short transfusion group) will be significantly different from the change in babies who receive platelets over two hours (long transfusion group) when platelets are checked immediately after transfusion and 6 hours after the completion of transfusion. 2. We also expect there to be significant differences in the platelet counts drawn thirty minutes after transfusion compared to the counts drawn 6 hours after the completion of the transfusion in either group.

Conditions

• Thrombocytopenia

Interventions

Type	Name	Description
PROCEDURE	Short platelet transfusion	15cc/kg of non-centrifuged, non-refrigerated, leukoreduced, AB-negative pheresis platelets administered over 30 minutes
PROCEDURE	Long platelet transfusion	15cc/kg of non-centrifuged, non-refrigerated, leukoreduced, AB-negative pheresis platelets given over two hours.

Timeline

• Start date: 2009-05-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2009-07-29
• Last updated: 2011-07-12
• Results posted: 2011-07-12

Locations

1 site across 1 country: United States