NCT00947323

Simvastatin for Treating Erectile Dysfunction

The Effect of Simvastatin in the Penile Erection: a Randomized, Double-blind Clinical Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Santa Casa de Porto Alegre · Academic / Other
• Sex: Male
• Age: 35 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized clinical trial, double-blind, placebo controlled, to verify if simvastatin can improve erectile dysfunction in men with endothelial dysfunction, without any cardiac disease.It is hypothesized that the simvastatin can improve the endothelial function, improving the nitric oxide liberation in corpora cavernosa of the penis, resulting in improvement of erection.

Conditions

• Erectile Dysfunction
• Vascular Disease Detected
• C Reactive Protein

Interventions

Type	Name	Description
DRUG	Simvastatin	simvastatin 20 daily for six months.
DRUG	Placebo

Timeline

• Start date: 2006-01-01
• Primary completion: 2008-07-01
• Completion: 2008-12-01
• First posted: 2009-07-28
• Last updated: 2010-09-27