NCT00944853

Effects of Liquid Zinc Supplementation and Dispersible Zinc Tablets on Plasma Zinc Concentration

The Effect of Zinc Supplementation, Provided as Either a Liquid Zinc Solution or Dispersible Tablets, on Plasma Zinc Concentration Among Young Burkinabe Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 462 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 6 Months – 23 Months
• Healthy volunteers: Accepted

Summary

The study aims to compare the effects of two different formulations of zinc supplements on plasma zinc concentrations among young Burkinabe children.

Detailed description

1\) To investigate the effects of short-term zinc supplementation, provided either as a dispersible tablet containing zinc sulfate ("ZinCfant," Nutriset Ltd; Malaunay, France) or as a liquid ZnSO4 solution, on changes in serum zinc concentration, compared with a placebo in young Burkinabe children; and 2) to assess the relationship between change in serum zinc concentration and the presence of altered intestinal permeability within each treatment group.

Conditions

• Zinc Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Liquid zinc syrup	Liquid zinc syrup containing 5 mg zinc as zinc sulfate
DIETARY_SUPPLEMENT	Zinc tablet	Dispersible zinc tablet containing 5 mg zinc
DIETARY_SUPPLEMENT	Liquid placebo supplement	Liquid placebo supplement containing 0 mg zinc

Timeline

• Start date: 2009-08-01
• Primary completion: 2009-12-01
• Completion: 2010-02-01
• First posted: 2009-07-23
• Last updated: 2017-02-24

Locations

1 site across 1 country: Burkina Faso