Trials / Completed
CompletedNCT00944736
Effect of VSL#3 on Intestinal Permeability in Pediatric Crohn's Disease
Effect of Probiotic VSL#3 on Intestinal Permeability of Pediatric Patients With Crohn's Disease in Remission
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Children's Mercy Hospital Kansas City · Academic / Other
- Sex
- All
- Age
- 11 Years – 17 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the effect of a probiotic formulation, VSL#3, on intestinal permeability in pediatric patients with Crohn's disease.
Detailed description
Children with Crohn's disease have altered intestinal permeability. A pilot study in children showed that probiotics may decrease intestinal permeability. In this double blind, randomized controlled trial, we will observe the effect of VSL#3 on small bowel permeability using a double sugar absorption test. PCDAI was monitored, but not analyzed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | VSL#3 | 1 packet BID |
| DIETARY_SUPPLEMENT | Placebo | 1 inactive packet BID |
Timeline
- Start date
- 2009-07-01
- Primary completion
- 2012-07-01
- Completion
- 2013-07-01
- First posted
- 2009-07-23
- Last updated
- 2014-03-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00944736. Inclusion in this directory is not an endorsement.