NCT00941525

Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 174 (actual)
• Sponsor: Aristotle University Of Thessaloniki · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether 24-hour fluctuation of intraocular pressure (IOP) is associated with central corneal thickness (CCT) in subjects with ocular hypertension or open angle glaucoma and in age-matched controls. Also to evaluate whether mean IOP reduction as a response to latanoprost (0.005% Xalatan) is associated with CCT, after a 4-weeks period of treatment. Also, to evaluate whether 24-hour fluctuation of IOP is associated with corneal hysteresis (CH) measured by Ocular Response Analyzer (ORA).

Conditions

• Open Angle Glaucoma
• Ocular Hypertension

Interventions

Type	Name	Description
DRUG	Latanoprost	1 eyedrop of latanoprost (0.005%) dosed once a day at 8:00pm for a 4-weeks period

Timeline

• Start date: 2009-09-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2009-07-17
• Last updated: 2015-07-07

Locations

1 site across 1 country: Greece