NCT00936728

White Wine or Nutritional Supplement in Improving Appetite in Patients With Cancer

White Wine for Appetite Loss: A Randomized, Controlled, Non-Blinded Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: Academic and Community Cancer Research United · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

RATIONALE: It is not yet know whether white wine is more effective than a nutritional supplement in improving appetite. PURPOSE: This randomized clinical trial is studying white wine to see how well it works compared with a nutritional supplement in improving appetite in patients with cancer

Detailed description

OBJECTIVES: I. To compare white wine (Arm A) to non-wine nutritional supplement (Arm B) for the treatment of cancer-associated anorexia. II. To evaluate the side effect profile of white wine (Arm A). OUTLINE: Patients are stratified according to primary malignant disease (lung vs gastrointestinal vs other \[specify\]), severity of weight loss (excluding peri-operative weight loss) within the past 2 months (\< 4.6 kg \[\< 10 lbs\] vs \>= 4.6 kg \[\>= 10 lbs\]), age (\< 50 years vs \>= 50 years), and planned concurrent chemotherapy or radiation (yes vs no). Patients are randomized to 1 of 2 arms. ARM A: Patients consume white wine with =\< 15% alcohol content twice daily for 3-4 weeks. ARM B: Patients receive an oral non-wine nutritional supplement (e.g., Boost or Ensure) twice daily for 3-4 weeks. After completion of study treatment, patients are followed up every 6 months for 2 years.

Conditions

• Unspecified Adult Solid Tumor, Protocol Specific

Interventions

Type	Name	Description
OTHER	therapeutic nutritional supplementation	Given orally
DIETARY_SUPPLEMENT	white wine	Given orally
OTHER	questionnaire administration	Ancillary studies

Timeline

• Start date: 2009-07-01
• Primary completion: 2017-03-02
• Completion: 2017-04-17
• First posted: 2009-07-10
• Last updated: 2023-02-01

Locations

4 sites across 1 country: United States