NCT00935350

Reduction of the Glycemic Index by a Novel Viscous Polysaccharide

Effect of Adding the Novel Fiber, PGX®,to Commonly Consumed Foods on Glycemic Response and Glycemic Index: A Practical and Effective Strategy for Reducing Post Prandial Blood Glucose Levels.

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Glycemic Index Laboratories, Inc · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Reductions of postprandial glucose levels have been demonstrated previously with the addition of a novel viscous polysaccharide (NVP) to a glucose drink and standard white bread. This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods.

Detailed description

Recently, a commercial novel viscous polysaccharide (NVP)complex has been developed which is marketed in both the USA and Canada under the trade name PGX® (PolyGlycopleX) (InovoBiologic Inc, Calgary, AB, Canada). This complex consists of three viscous non starch polysaccharides which are processed using proprietary technology (EnviroSimplex®) to produce compressed granules which delays the onset of viscosity and increases palatability of the fiber when added to food. Previously, this fibre was shown to lower postprandial glucose levels in a dose responsive manner when mixed with a glucose drink and sprinkled onto a standard white bread demonstrating that the processing did not interfere with the effectiveness of the fiber. From this study the reduction in GI was calculated to be 7 units per gram of NVP when added to a solid food, however it is not known whether this relationship would be maintained when the NVP was added to a range of commonly eaten foods. This study therefore evaluates the effect of the addition or incorporation of NVP into a range of foods on postprandial glycemia and whether the reductions in glycemic index could be predicted using.

Conditions

• Blood Glucose, Postprandial

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	PolyGlycopleX (PGX)	2.5 grams of PGX
DIETARY_SUPPLEMENT	PolyGlycopleX (PGX)	5.0 grams of PGX
DIETARY_SUPPLEMENT	PolyGlycopleX (PGX)	0 grams of PGX

Timeline

• Start date: 2006-05-01
• Primary completion: 2006-06-01
• Completion: 2006-08-01
• First posted: 2009-07-09
• Last updated: 2009-07-09

Locations

1 site across 1 country: Canada