NCT00933634

Efficacy and Safety of Electrical Versus Pharmacological Cardioversion in Early Atrial Fibrillation

Efficacy and Safety of Electrical Versus Pharmacological Cardioversion in Early Atrial Fibrillation: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 247 (estimated)
• Sponsor: Valduce Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The optimal strategy to restore sinus rhythm in patients with atrial fibrillation (AF) of less than 48 hours' duration is still controversial. The investigators performed a controlled single-center trial to compare electrical and pharmacological (propafenone) cardioversion to restore the sinus rhythm in selected patients with acute atrial fibrillation.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
PROCEDURE	electrical cardioversion	External cardioversion was performed in anteroposterior position (right sternal body at the third intercostal space-angle of the left scapula); patients were submitted to a biphasic wave-form sequential shock of 100-150-200 J, if necessary.
DRUG	propafenone	Propafenone (2 mg/kg bolus) was administered to obtain pharmacolgic sinus rhythm conversion.

Timeline

• Start date: 2006-01-01
• Primary completion: 2008-11-01
• Completion: 2008-11-01
• First posted: 2009-07-07
• Last updated: 2009-07-07

Locations

1 site across 1 country: Italy