Clinical Trials Directory

Trials / Completed

CompletedNCT00932971

HIDIT II - PegIFN-alfa2a Plus Tenofovir in Chronic Delta Hepatitis

A Multicenter Randomised Study Comparing the Efficacy of PegIFN-alfa2a Plus Placebo vs. PegIFN-alfa2a Plus Tenofovir for the Treatment of Chronic Delta Hepatitis-The Hep-Net International Delta Hepatitis Interventional Trial II (HIDIT-II)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
70 (actual)
Sponsor
HepNet Study House, German Liverfoundation · Network
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Randomized, double blind study comparing the efficacy of pegylated interferon-alfa2a plus placebo versus pegylated interferon-alfa2a plus tenofovir for the treatment of chronic delta hepatitis. 70 Patients will be randomized 1:1 into the two groups. Treatment duration: 96 weeks. Follow-up: 24 weeks. Long-term-follow-up: until week 358.

Conditions

Interventions

TypeNameDescription
DRUGPEG-IFN alfa-2a, TenofovirPegylated interferon alfa-2a, 180µg once weekly, subcutaneously; Tenofovir disoproxilfumarat, 245mg, once daily, orally
DRUGPEG-IFN alfa-2a, placeboPegylated interferon alfa-2a, 180µg once weekly, subcutaneously; Placebo, once daily, orally

Timeline

Start date
2009-06-01
Primary completion
2017-08-01
Completion
2017-08-02
First posted
2009-07-07
Last updated
2018-01-29

Locations

10 sites across 3 countries: Germany, Greece, Romania

Source: ClinicalTrials.gov record NCT00932971. Inclusion in this directory is not an endorsement.