NCT00927771

Azelaic Acid Versus Hydroquinone in Melasma

Efficacy & Safety of Azelaic Acid 15% Gel vs. Hydroquinone 4% Cream in the Treatment of Melasma

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Callender Center for Clinical Research · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the safety and effectiveness of Azelaic Acid Gel to Hydroquinone Cream in the treatment of melasma.

Detailed description

Melasma is a chronic condition in which dark areas appear on the forehead, cheeks, and upper lips. Hydroquinone is a skin lightener (or fade cream) and is one of the most commonly used medications for the treatment of melasma. Azelaic acid gel is currently used to treat acne and rosacea.

Conditions

• Melanosis

Interventions

Type	Name	Description
DRUG	azelaic acid gel	azelaic acid 15% gel twice a day for 6 months
DRUG	hydroquinone cream	hydroquinone 4% cream twice a day for 6 months

Timeline

• Start date: 2009-06-01
• Primary completion: 2010-06-01
• Completion: 2010-12-01
• First posted: 2009-06-25
• Last updated: 2009-06-25

Locations

1 site across 1 country: United States