NCT00927628

Macular Hole Reopening

Incidence and Factors Related to Macular Hole Reopening

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 831 (actual)
• Sponsor: Shinjo Ophthalmologic Institute · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: —

Summary

The purpose of this investigation was to determine the incidence and the factors that cause a reopening of a macular hole (MH) after a surgical closure.

Detailed description

A reopening of a macular hole (MH) is a well-known complication of successfully closed MHs. Recently, internal limiting membrane (ILM) peeling has become widely used as an adjunctive procedure during MH surgery. The incidence of a reopening of a MH is 0 to 8.6% in eyes in which the ILM was peeled off, and 2 to 16% in which the ILM was not peeled off. Part of the variation in the percentages of reopening was the length of the follow-up period; eyes with longer follow-up periods have higher incidences of reopening.

Conditions

• Vitrectomy

Interventions

Type	Name	Description
PROCEDURE	Vitrectomy	Patients underwent vitrectomy with or without internal limiting membrane (ILM) peeling for an idiopathic full-thickness macular holes. Simultaneous phacoemulsification with intraocular lens implantation was performed on all phakic patients who were \>40-years-of-age.

Timeline

• Start date: 1990-10-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2009-06-25
• Last updated: 2009-06-25

Locations

1 site across 1 country: Japan