NCT00927563

Tolcapone Treatment of Pathological Gambling

Tolcapone Treatment of Pathological Gambling: An Open-Label Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 21 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The goal of the proposed study is to evaluate the efficacy and safety of tolcapone in pathological gambling.

Detailed description

The proposed study will consist of 8 weeks of treatment with tolcapone in 10 subjects with pathological gambling. The hypothesis to be tested is that tolcapone will be effective in reducing the urges to gamble in patients with pathological gambling. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Conditions

• Pathological Gambling

Interventions

Type	Name	Description
DRUG	Tolcapone	pill, 100-300mg/day for 8 weeks

Timeline

• Start date: 2009-06-01
• Primary completion: 2012-05-01
• Completion: 2012-07-01
• First posted: 2009-06-25
• Last updated: 2023-02-23
• Results posted: 2014-03-06

Locations

1 site across 1 country: United States