NCT00926861

Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD

Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative AMD to Develop Exudative AMD

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 320 (estimated)
• Sponsor: The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Choroidal neovascularisation in age related macular degeneration is one of the major causes of legal blindness in the western world existing in two major occurences, the dry and the wet form.The etiology of age related macular degeneration is yet unknown. Genetic factors, oxidative stress, Ischaemia, and aging of the retinal pigment epithelium are discussed as etiologic factors. The risk of rapid vision loss is much higher in wet AMD, a dry form may transform to a wet form. From a prior study the investigators know that the posterior hyaloid is significantly more frequent attached in wet AMD. This study is conducted to examine whether the attached posterior hyaloid is a risk factor to develop wet AMD in dry AMD cases.

Conditions

• Dry Age-related Macular Degeneration
• Detachment of the Posterior Hyaloid

Interventions

Type	Name	Description
DEVICE	ultrasound	A-scan and B-scan ultrasound at baseline and month 6,12,24
DEVICE	OCT	Volume scans of spectralis OCT at baseline and month 6,12,24

Timeline

• Start date: 2009-07-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2009-06-24
• Last updated: 2010-06-09

Locations

1 site across 1 country: Austria