Clinical Trials Directory

Trials / Terminated

TerminatedNCT00926575

Study of orBec® With Prednisone Therapy in the Treatment of Patients With Graft Versus Host Disease (GVHD)

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Safety and Efficacy of orBec® (Oral Beclomethasone 17,21-Dipropionate)in Conjunction With Ten Days of High-Dose Prednisone Therapy in the Treatment of Patients With Gastrointestinal GVHD

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
140 (actual)
Sponsor
Soligenix · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Use of an oral topically-active glucocorticoid with limited side effects will control the gastrointestinal inflammatory process of GVHD and minimize glucocorticoid exposure.

Conditions

Interventions

TypeNameDescription
DRUGoral beclomethasone 17,21-dipropionateTwo tablets QID for 50 days
DRUGPlaceboTwo tablets QID for 50 days

Timeline

Start date
2009-10-01
Primary completion
2011-12-01
Completion
2012-05-01
First posted
2009-06-23
Last updated
2013-12-06
Results posted
2013-12-06

Locations

3 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00926575. Inclusion in this directory is not an endorsement.