NCT00923000

Herb Drug Interaction of Traditional Chinese Herb and Commonly Used Drugs

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Tri-Service General Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study was to investigate a possible response to nalbuphine (Nubian) and morphine with traditional Chinese herbs in healthy volunteers.

Detailed description

This study is a single center and open-label design to investigate the pharmacokinetic properties of Nubian, Nubian traditional Chinese herb combination dosage after single oral with oral administration, or morphine, morphine traditional Chinese herb combination dosage after single oral administration in healthy volunteers under fasting conditions.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Nalbuphine	Nalbuphine 10mg with oral administration
DRUG	Morphine	Morphine 10mg with oral administration
DRUG	Morphine with Long dan xie gan tang	Morphine 10mg with oral administration
DRUG	Nalbuphine with Long dan xie gan tang	Nalbuphine 10mg with Long dan xie gan tang 3g tid with oral administration
DRUG	Nubian with Long dan xie gan tang	Nalbuphine 10mg with Long dan xie gan tang 3g with oral administration

Timeline

• Start date: 2008-12-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2009-06-18
• Last updated: 2009-06-19

Locations

1 site across 1 country: Taiwan