Clinical Trials Directory

Trials / Completed

CompletedNCT00921869

A Study of E7050 Administered Orally to Patients With Advanced Solid Tumors

A Phase I Dose-finding Study of E7050 Administered Orally to Patients With Advanced Solid Tumors.

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Eisai Co., Ltd. · Industry
Sex
All
Age
20 Years – 74 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD) and anti-tumor activity of E7050 when administered orally twice daily to patients with advanced solid tumors.

Detailed description

Phase I, open-label, dose-escalation study to determine the maximum tolerated dose (MTD) of E7050 given orally, twice-daily, in patients with advanced tumors that have progressed following effective therapy.

Conditions

Interventions

TypeNameDescription
DRUGE7050The starting dose of E7050 will be 50 mg given orally, twice-daily, in patients with advanced tumors that have progressed following effective therapy.

Timeline

Start date
2009-10-01
Primary completion
2011-06-01
Completion
2011-06-01
First posted
2009-06-16
Last updated
2017-12-26

Locations

1 site across 1 country: Japan

Source: ClinicalTrials.gov record NCT00921869. Inclusion in this directory is not an endorsement.