NCT00921492

Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome

Does Low-frequency Electro-acupuncture Restore Sensitivity of the Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Göteborg University · Academic / Other
• Sex: Female
• Age: 18 Years – 39 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis The overall hypothesis is that non-obese (BMI \<30) women with PCOS have high luteinising hormone (LH) and cortisol pulse frequency and amplitude and that repeated low-frequency EA restore these alterations and induce ovulation.

Detailed description

Aim 1. Elucidate if low-frequency EA induce ovulation and restore LH frequency and amplitude as well as sex steroid secretion as compared to a control group receiving same amount of attention. Aim 2. Elucidate if low-frequency EA restore cortisol frequency and amplitude compared to a control group receiving same amount of attention. Aim 3. Elucidate if low-frequency EA restore psychological distress and quality of life as compared to a control group receiving same amount of attention.in women with PCOS.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
DEVICE	Low-frequency electro-acupuncture (EA)	2 Hz EA during 30 minutes, twice a week, 14 weeks.
OTHER	Meeting a therapist - attention control	Meeting a therapist, twice a week during 30 minutes in order to control for the increased amount of attention.

Timeline

• Start date: 2009-02-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2009-06-16
• Last updated: 2018-08-15

Locations

1 site across 1 country: Sweden