NCT00920569

Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation

Measurement of Recirculation, Oxygenator Blood Volume and Cardiac Output in ECMO Using a Modified Transonic Systems (tm) HD02 Monitoring System

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: Transonic Systems Inc. · Industry
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is to test the usefulness of ultrasound dilution measurements in patients on extracorporeal membrane oxygenation. Measurements may include; efficiency of support (recirculation), amount of clotting in the oxygenator (oxygenator blood volume), and how well the heart is working (cardiac output). At the present time there are no devices available to perform these functions.

Detailed description

At the present time there are no devices available to measure recirculation, oxygenator blood volume and cardiac output in patients on extracorporeal membrane oxygenation. The study uses an external monitor, laptop computer, clamp on flowsensors and ultrasound dilution technology to measure blood flow. Measurements are made by injecting 0.5 - 1 ml/kg of sterile isotonic saline into the patient's extracorporeal circuit. The subject will be monitored throughout the measurements. The measurements will be coordinated with the regular care of the extracorporeal circuit.

Conditions

• Recirculation
• Oxygenator Blood Volume
• Cardiac Output
• Venoarterial Extracorporeal Membrane Oxygenation
• Venovenous Extracorporeal Membrane Oxygenation

Timeline

• Start date: 2006-05-01
• Primary completion: 2008-08-01
• Completion: 2008-08-01
• First posted: 2009-06-15
• Last updated: 2016-05-27

Locations

1 site across 1 country: United States