NCT00919880

Comparison of Neo-adjuvant Weekly Paclitaxel With or Without Carboplatin in Early Breast Cancer

A Phase II Randomized Clinical Trial of Neo-adjuvant Weekly Paclitaxel With or Without Carboplatin in Early Breast Cancer

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 148 (actual)
• Sponsor: Tao OUYANG · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether neo-adjuvant weekly paclitaxel with carboplatin is better than paclitaxel alone in efficiency and safety in early breast cancer, and to explore whether ultrasound and magnetic resonance imaging can predict the efficiency of neo-adjuvant chemotherapy.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	carboplatin+ paclitaxel	carboplatin AUC 2mg/mL\*min/week, 3 week cycle up to 4 cycles; paclitaxel 80mg/m2/week, 3 week cycle up to 4 cycles
DRUG	paclitaxel	paclitaxel 80mg/m2/week, 3 week cycle up to 4 cycles

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-07-01
• Completion: 2010-12-01
• First posted: 2009-06-12
• Last updated: 2014-08-15

Locations

1 site across 1 country: China