NCT00919451

Ciclosporin in the Management of Steroid Resistant Type 1 Reactions in Leprosy

A Pilot Study Assessing the Efficacy and Safety of Ciclosporin as a Second -Line Drug in Patients With Type 1 Reactions Who Have Not Responded to a 12 Week Course of Prednisolone.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: London School of Hygiene and Tropical Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Study 1B: Ciclosporin in the management of steroid resistant Type 1 Reactions in Leprosy Objective: A pilot study assessing the efficacy and safety of Ciclosporin as a second -line drug in patients with Type 1 Reactions who have not responded to a 12 week course of Prednisolone.

Conditions

• Leprosy

Interventions

Type	Name	Description
DRUG	ciclosporin	Ciclosporin 7.5mg/kg - reducing regimen over 24 weeks (additional prednisolone given for the first four weeks)

Timeline

• Start date: 2010-08-01
• Primary completion: 2013-06-01
• Completion: 2013-07-01
• First posted: 2009-06-12
• Last updated: 2015-03-25

Locations

1 site across 1 country: Ethiopia