NCT00918892

Assessment of Candidate Protein Expression in Breast Cancer Specimens

Assessment of Candidate Protein Expression in Human Breast Cancer Specimens

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 460 (actual)
• Sponsor: Case Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

RATIONALE: Studying the genes expressed in samples of tumor tissue from patients with cancer may help doctors identify biomarkers related to cancer. PURPOSE: This research study is looking at tumor tissue samples from patients who have undergone surgery for breast cancer.

Detailed description

OBJECTIVES: * To determine if candidate genes display differential expression between normal and cancer breast tissues. OUTLINE: Previously collected breast cancer tissue samples (paraffin embedded blocks) and normal adjacent tissue are used for immunohistochemistry studies of expression of candidate genes.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
GENETIC	gene expression analysis	Previously collected breast cancer tissue samples (paraffin embedded blocks) and normal adjacent tissue are used for immunohistochemistry studies of expression of candidate genes.
OTHER	immunohistochemistry staining method	Previously collected breast cancer tissue samples (paraffin embedded blocks) and normal adjacent tissue are used for immunohistochemistry studies of expression of candidate genes.
OTHER	laboratory biomarker analysis	Previously collected breast cancer tissue samples (paraffin embedded blocks) and normal adjacent tissue are used for immunohistochemistry studies of expression of candidate genes.

Timeline

• Start date: 2011-01-01
• Primary completion: 2021-09-23
• Completion: 2021-09-23
• First posted: 2009-06-11
• Last updated: 2022-08-01

Locations

1 site across 1 country: United States