NCT00917137

Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy

Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy: Yield and Predictors of a Positive Aspirate

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Maggiore Bellaria Hospital, Bologna · Academic / Other
• Sex: All
• Age: 18 Years – 76 Years
• Healthy volunteers: Not accepted

Summary

The main purposes of this study are to assess the performance characteristics of transbronchial needle aspiration (TBNA) in the diagnosis of peripheral pulmonary lesions, and to identify the predictor variables of a positive aspirate.

Detailed description

In a recent systematic literature review (Rivera PM, Mehta AC; Chest 2007; 132: 1318-1488) TBNA showed the highest sensitivity in the diagnostic bronchoscopic approach to peripheral pulmonary lesions, as compared to the other available sampling techniques (transbronchial biopsy, brushing, washings). However, the Authors conclude that the data regarding TBNA in this setting deserve cautious interpretation because of the limited number of studies and the large differences in sample size). We designed the present study to assess the performance characteristics of TBNA, alone and in comparison with those of transbronchial biopsy, in the diagnosis of peripheral pulmonary lesions.

Conditions

• Pulmonary Nodule
• Pulmonary Mass

Interventions

Type	Name	Description
PROCEDURE	TBNA + transbronchial lung biopsy + bronchial washing

Timeline

• Start date: 2008-07-01
• Primary completion: 2010-06-01
• Completion: 2010-06-01
• First posted: 2009-06-10
• Last updated: 2010-06-23

Locations

1 site across 1 country: Italy