NCT00915967

Prevention of Neurosurgical Wound Infections

Pilot Project: Prevention of Neurosurgical Wound Infections

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 214 (actual)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to determine whether injecting the antibiotic vancomycin directly into surgical wounds can decrease the rate of infection following implantation of neurosurgical devices.

Conditions

• Surgical Wound Infections

Interventions

Type	Name	Description
DRUG	Vancomycin	Subjects randomized to the vancomycin group will receive an injection (up to 10 mL) of 5 mg/mL vancomycin administered directly into the wound with a blunt needle following watertight fascial closure.
DRUG	Placebo (Saline Solution)	Subjects randomized to the saline group will receive an injection (up to 10 mL) of saline solution directly into the wound following watertight fascial closure.

Timeline

• Start date: 2009-05-13
• Primary completion: 2014-12-19
• Completion: 2014-12-19
• First posted: 2009-06-08
• Last updated: 2019-04-30
• Results posted: 2019-04-30

Locations

1 site across 1 country: United States