NCT00915499

Complex Sleep Apnea Syndrome (CompSAS) Resolution Study

Is Adaptive Servo-Ventilation Therapeutically More Effective Than Continuous Positive Airway Pressure In Treating Complex Sleep Apnea Syndrome?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: ResMed · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether adaptive servo-ventilation (ASV) or continuous positive airway pressure (CPAP) is better at treating complex sleep apnea over time.

Detailed description

Between 3 and 19% of patients with clinical and polysomnographic features of obstructive sleep apnea syndrome (OSA) develop a high-frequency of central apneas and/or disruptive Cheyne-Stokes respiratory syndrome after application of continuous positive airway pressure (CPAP), a pattern called the complex sleep apnea syndrome (CompSAS). The trial seeks to determine the efficacy of the ASV vs. CPAP modes for the treatment of CompSAS over time. Baseline clinical and laboratory data will be collected, patients will be randomized to one of the two treatments. Overall study participation is approximately 3 months.

Conditions

• Complex Sleep Apnea Syndrome

Interventions

Type	Name	Description
DEVICE	VPAP Adapt SV	Comparison of ASV and CPAP modes

Timeline

• Start date: 2009-05-01
• Primary completion: 2011-10-01
• Completion: 2011-12-01
• First posted: 2009-06-08
• Last updated: 2013-02-28
• Results posted: 2013-02-22

Locations

6 sites across 1 country: United States