NCT00915421

Pre-Hospital Cooling in Cardiac Arrest Patients

Pre-Hospital Cooling in Cardiac Arrest Patients - Feasibility Pilot Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Emergency Medical Service of the Central Bohemian Region, Czech Republic · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Type of study: Pilot prospective nonrandomized feasibility clinical study. Aim of the study: To assess the feasibility of pre-hospital therapeutic mild hypothermia in patients successfully resuscitated from out-of-hospital cardiac arrest in the setting of prehospital and hospital care in Czech republic. Evaluated hypothesis: Pre-hospital initiation of therapeutic mild hypothermia by rapid administration of intravenous bolus of cold crystalloids is simple, safe, effective and is a feasible procedure to significantly decrease body core temperature during patient's transport to the hospital in Czech republic. The study is observational and does not evaluate any new drug, therapeutic procedure or diagnostic procedure. It is evaluating a known therapeutic procedure, therapeutic mild hypothermia, induced by known technique, cold crystalloid infusion, widely accepted in hospital-related postresuscitative care. However, even its prehospital usage has been published.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
PROCEDURE	Induction of therapeutic mild hypothermia	Rapid administration of 4°C cold normal saline to the peripheral vein, dose 5 - 30 ml/kg, to decrease body core temperature below 34°C

Timeline

• Start date: 2007-07-01
• Primary completion: 2009-07-01
• Completion: 2009-08-01
• First posted: 2009-06-08
• Last updated: 2009-06-08

Locations

2 sites across 1 country: Czechia