Clinical Trials Directory

Trials / Unknown

UnknownNCT00915369

A Clinical Trial to Study the Effects of Nanoparticle Based Paclitaxel Drug, Which Does Not Contain the Solvent Cremophor, in Advanced Breast Cancer

A Multicentre Phase I Study Of Cremophor FreePaclitaxel Nanoparticle In Advanced Breast Cancer

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Fresenius Kabi Oncology Ltd. · Industry
Sex
Female
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

This study is a multicentre, open label, non-randomized phase I study. The main objectives of the study are to determine the pharmacokinetic profile of the drug at different dose levels in the patients with Advanced Breast Cancer. Maximum Tolerated Dose (MTD) and safety of Paclitaxel Nanoparticle will also be simultaneously assessed.

Conditions

Interventions

TypeNameDescription
DRUGNanoxel (Paclitaxel Nanoparticle formulation )Nanoxel (Nanoparticle Paclitaxel) at 4 different dose levels of 220, 260, 310 and 375 mg/m2. Each patient will recieve upto 6 cycles.

Timeline

Start date
2009-03-01
Primary completion
2010-04-01
Completion
2010-04-01
First posted
2009-06-08
Last updated
2010-02-08

Locations

3 sites across 1 country: India

Source: ClinicalTrials.gov record NCT00915369. Inclusion in this directory is not an endorsement.