Trials / Completed
CompletedNCT00913328
Effect of Add-on Montelukast to Inhaled Corticosteroids on Airway Responsiveness
Effect of Add-on Montelukast to Inhaled Corticosteroids in Excessive Airway Narrowing in Adults With Asthma
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- Hvidovre University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
Leukotriene receptor antagonists appear to posses additive anti-inflammatory effects to the effect of inhaled corticosteroids. Hypothesis: Treatment with oral montelukast will lower the dose-response plateau to inhaled methacholine in patients with mild to moderate persistent asthma treated with a stable dose of inhaled corticosteroids.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Montelukast (Singulair) | 10 mg tablet once daily |
| DRUG | Placebo | Oral placebo once daily |
Timeline
- Start date
- 2002-08-01
- Primary completion
- 2006-05-01
- Completion
- 2006-10-01
- First posted
- 2009-06-04
- Last updated
- 2009-06-04
Source: ClinicalTrials.gov record NCT00913328. Inclusion in this directory is not an endorsement.