NCT00913315

Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis

Efficacy Study of Tamsulosin and Tolterodine Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Lower Urinary Tract Symptoms

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Chongqing Medical University · Academic / Other
• Sex: Male
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether tamsulosin and tolterodine are effective in the treatment of men with lower urinary tract symptoms and chronic prostatitis/chronic pelvic pain syndrome.

Detailed description

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in urological clinics. Most of the clinically CP/CPPS are to some extent associated with storage (irritative) symptoms, such as increased frequency, urgency, and nocturia, namely many patients with CP/CPPS have overactive bladder symptoms. Alpha-blocker therapy has been advocated as a treatment modality for CP/CPPS. Some trials showed a statistically and likely clinically significant treatment effect, while other trials showed no benefit. Therefore, tamsulosin combination with tolterodine treatment for CP/CPPS may be more effective than tamsulosin single.

Conditions

• Prostatitis

Interventions

Type	Name	Description
DRUG	tolterodine	4 mg of tolterodine ER
DRUG	tamsulosin	0.4 mg of tamsulosin once a day for 8 weeks
DRUG	placebo	placebo once a day for 8 weeks

Timeline

• Start date: 2009-08-01
• Primary completion: 2009-10-01
• Completion: 2010-01-01
• First posted: 2009-06-04
• Last updated: 2009-06-05

Locations

1 site across 1 country: China