NCT00912158

Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema

CPAP Versus BiPAP in Acute Cardiogenic Pulmonary Edema: Experience With 129 Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 129 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cardiogenic pulmonary edema (CPE) is a common medical emergency and noninvasive ventilation (NIV) in addition to conventional medical treatment might be beneficial for patients with CPE.

Detailed description

To evaluate the effect of adding continuous positive airway pressure (CPAP) or bilevel positive airway pressure (BiPAP) to standard medical therapy (ST) on intensive care unit (ICU) stay, hospital stay, mortality, need for endotracheal intubation, partial arterial O2 tension (PaO2), intrapulmonary shunt, alveolar-arterial (A-a) oxygen gradient, and cardiac output in patients admitted to the respiratory intensive care unit (ICU) or cardiac care unit (CCU) with acute CPE with gas exchange abnormalities and to evaluate the impact of heart failure type on the outcome of different therapeutic schedules.

Conditions

• Acute Cardiogenic Pulmonary Edema

Interventions

Type	Name	Description
OTHER	standard therapy (ST)	standard medical therapy
DEVICE	CPAP	Non-invasive mechanical ventilation (CPAP)
DEVICE	BIPAP	Non-invasive mechanical ventilation (BIPAP)

Timeline

• Start date: 2003-10-01
• Primary completion: 2007-11-01
• Completion: 2007-11-01
• First posted: 2009-06-03
• Last updated: 2009-09-04
• Results posted: 2009-06-03

Locations

1 site across 1 country: Egypt