NCT00911664

Vitamin D Supplementation and CD4 Count in HIV-Infected Children

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: The Hospital for Sick Children · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

To find out if vitamin D supplementing can lead to an improvement in immunological status in HIV-infected children as part of routine clinical care

Detailed description

The objective of this study is to determine the impact of vitamin D on immunological status in HIV-infected children as measured by CD4 count (CD4 percent). We will determine if vitamin D supplementation leads to a measurable change in CD4 count (CD4 percent) in HIV-infected children in the context of routine clinical care. Specific study questions are: 1. Does vitamin D supplementation lead to a change in CD4 percent (CD4 count) in HIV-infected children? 2. Do the serum levels of the active form of vitamin D \[1, 25(OH)2D and 25(OH)D\] correlate with CD4 percent (CD4 count) in HIV-infected children?

Conditions

• HIV

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin D	Weekly dose of 5600 IU (800 IU per day)
DRUG	No supplementation	Control
DIETARY_SUPPLEMENT	Vitamin D	Weekly dose of 11,200 IU (1600 IU per day)

Timeline

• Start date: 2009-02-01
• Primary completion: 2009-10-01
• Completion: 2010-07-01
• First posted: 2009-06-02
• Last updated: 2014-06-06

Locations

1 site across 1 country: Canada