NCT00905996

Primary Prophylaxis of Gastric Varix Bleed

A Randomized Controlled Trial Comparing Cyanoacrylate Injection Versus Beta-Blockers Versus No Treatment for Primary Prophylaxis of Gastric Variceal Bleed

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Govind Ballabh Pant Hospital · Other Government
• Sex: All
• Age: 12 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

In patients who have never bled from gastric varix (GOV2 and IGV1), cyanoacrylate injection will be better than both beta-blocker therapy and no treatment in prevention of gastric variceal bleed. The investigators conducted a randomized controlled trial in patients with gastric varix (GOV2 and IGV1) who never bled before, to study the efficacy of treatment with cyanoacrylate injection versus beta-blocker versus no treatment in prevention of first bleed from gastric varices.

Detailed description

Patients are followed up every 3 months or at the time of end point or complications.

Conditions

• Cirrhosis

Interventions

Type	Name	Description
PROCEDURE	Endoscopic cyanoacrylate injection	Endoscopic cyanoacrylate injection in gastric varix
DRUG	Beta-blocker (propranolol)

Timeline

• Start date: 2006-08-01
• Primary completion: 2009-01-01
• Completion: 2009-01-01
• First posted: 2009-05-21
• Last updated: 2009-05-21

Locations

1 site across 1 country: India