NCT00905723

The Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women

Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: Female
• Age: 45 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Climacterium is marked by hypoestrogenism and it is associated to drastic vasomotors symptoms, genital atrophy and humor alteration. Additionally, these symptoms impair sexual life and life quality. These effects can be counteracted by administration of estrogen therapy. However, estrogen therapy has side effects and isoflavone has been proposed as an estrogen substitute in reposition therapy. The aim of the randomized controlled trial is to evaluate the effects of isoflavone in the sex life assessed by a modified McCoy's sexual questionnaire.

Conditions

• Postmenopausal Symptoms

Interventions

Type	Name	Description
DRUG	estradiol	1 mg daily for 6 months
DRUG	isoflavone	150 mg isoflavone daily for 6 months
DRUG	Placebo	sugar pill daily for six months

Timeline

• Start date: 2009-05-01
• Primary completion: 2010-05-01
• First posted: 2009-05-20
• Last updated: 2009-05-20

Locations

1 site across 1 country: Brazil