Trials / Completed
CompletedNCT00905528
TRENDY Follow-up: Study on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
Prospective Study on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 69 (estimated)
- Sponsor
- University of Erlangen-Nürnberg Medical School · Academic / Other
- Sex
- All
- Age
- 30 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Basal nitric oxide (NO) activity plays a pivotal role in the regulation of glomerular hemodynamics, and in animal experiments its alteration has been associated with morphological changes characteristic of diabetic nephropathy. The investigators aimed to assess in a prospective study: 1. basal NO activity of renal vasculature and 2. renal hemodynamics to examine whether impairment of basal NO activity of the renal vasculature is related to development and progression of diabetic nephropathy and other cardiovascular endpoints.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Telmisartan 80 mg/d | |
| DRUG | Ramipril 10 mg/d |
Timeline
- Start date
- 2002-01-01
- Primary completion
- 2004-12-01
- Completion
- 2004-12-01
- First posted
- 2009-05-20
- Last updated
- 2015-03-25
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00905528. Inclusion in this directory is not an endorsement.