NCT00905229

Comparing Different Routes and Doses of Phytonadione (Vitamin K) for Reversing Warfarin Treated Patients With Hip Fracture Before Surgery

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: HaEmek Medical Center, Israel · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

It is well known that femoral neck fractures carry a significant increase in patients' mortality and that surgical intervention is the preferred treatment. Any delay in operating on such patients would inevitably increase their risk of developing complications. One of the reasons for such unintentional delay would be the hypercoagulative status of patients taking warfarin. The CHEST 2008 guidelines suggest reversing warfarin with Vitamin K for patients who need urgent operation. The aim of this study is to compare different roots and doses of Vitamin K.

Conditions

• Bleeding
• Complications

Interventions

Type	Name	Description
DRUG	Phytonadione	2.5 mg po
DRUG	Phytonadione	0.5 mg IV

Timeline

• Start date: 2009-05-01
• Primary completion: 2010-04-01
• Completion: 2010-04-01
• First posted: 2009-05-20
• Last updated: 2015-06-23

Locations

1 site across 1 country: Israel