NCT00901160

Thromboelastography (TEG®) and Platelet Function in Patients on Anti-platelet Agents

Pilot Study for the Prediction of Post-operative Thrombotic and Bleeding Complications in Non-cardiac Surgery Using Thromboelastography (TEG®) and Platelet Mapping Assay (PMA™) in Patients on Anti-platelet Agents

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: McMaster University · Academic / Other
• Sex: All
• Age: 40 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Can a post-operative analysis using a simple blood test (Thromboelastography(TEG®)) and Platelet Mapping Assay (PMA™) be able to detect the occurence of clotting or bleeding complications in patients on blood thinning (anti-platelet) agents?

Detailed description

Two hundred patients coming for surgery who are taking anti-platelet medications will be enrolled in this study as a pilot, to determine the feasibility for a larger study. A simple blood test for clotting function will be done after surgery. Patients will be assessed daily during their hospital stay to determine if they have any clotting or bleeding complications. For analysis, groups will be divided into normal and increased or decreased ability to make a blood clot based on the TEG® and PMA™ test done. Complications will be recorded for each group and analyzed to determine if there is any difference between groups.

Conditions

• Blood Clotting

Interventions

Type	Name	Description
PROCEDURE	blood test	Blood will be taken from patients shortly after surgery in the recovery room in order to perform Thromboelastography® and Platelet Mapping Assay™ tests.

Timeline

• Start date: 2008-01-01
• Primary completion: 2009-03-01
• Completion: 2011-06-01
• First posted: 2009-05-13
• Last updated: 2015-04-08

Locations

2 sites across 1 country: Canada