Clinical Trials Directory

Trials / Completed

CompletedNCT00900614

Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer

An Open-label Phase I Dose Escalating Study of APR-246 for Infusion in Patients With Refractory Hematologic Malignancies or Prostate Carcinoma

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
36 (actual)
Sponsor
Aprea Therapeutics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the highest feasible dose (HFD) of intravenous (IV) APR-246 when given to patients with refractory hematologic malignancies or prostate carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGAPR-246Intravenous infusion. Dose escalating. Dosing will be conducted with three patients at each dose level.

Timeline

Start date
2009-05-01
Primary completion
2010-10-01
Completion
2010-10-01
First posted
2009-05-13
Last updated
2019-07-31

Locations

6 sites across 1 country: Sweden

Source: ClinicalTrials.gov record NCT00900614. Inclusion in this directory is not an endorsement.