NCT00899587

Evaluation of the Effects of Oxygen Therapy and Enalapril for Diabetic Macular Ischemia

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: —
• Sponsor: Shahid Beheshti University of Medical Sciences · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

In this study, patients were divided into 3 group with 35 cases including: 1.oxygen 2.enalapril 3.control. In the beginning of the study, best corrected visual acuity (BCVA), uncorrected visual acuity (UCVA), and optical coherence tomography (OCT) were measured. Patients in the oxygen group were given oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month. In the enalapril group, patients were given enalapril 5 mg every night and placebo was given for the patients in third group. At the end of first month the patients' vision was checked again and at the the end of the third month the first physical examinations were performed. In the first group, arterial blood gas (ABG) was taken before and after oxygen therapy as well.

Conditions

• Diabetic Macular Ischemia

Interventions

Type	Name	Description
DRUG	enalapril	enalapril 5 mg every night
OTHER	oxygen	oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month
DRUG	placebo

Timeline

• First posted: 2009-05-12
• Last updated: 2009-05-12

Locations

1 site across 1 country: Iran