NCT00893074

The Effect of Prescription Medications in Marijuana Users

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

A subset of heavy marijuana users have trouble quitting marijuana use and the number of those seeking treatment for problems related to marijuana is increasing. The purpose of this research study is to investigate whether dronabinol can reduce withdrawal effects associated with stopping marijuana use, if dronabinol can reduce the rewarding effects of smoked marijuana, and whether there are any cognitive performance deficits associated with dronabinol doses that produce such effects.

Conditions

• Marijuana Abuse

Interventions

Type	Name	Description
DRUG	Dronabinol 30mg/day	10mg dronabinol administered 3x/day for 5 days
DRUG	Dronabinol 60mg/day	20mg dronabinol administered 3x/day for 5 days
DRUG	Dronabinol 120mg/day	40mg dronabinol administered 3x/day for 5 days
DRUG	Placebo	placebo dronabinol administered 3x/day for 5 days

Timeline

• Start date: 2009-04-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2009-05-05
• Last updated: 2017-08-03
• Results posted: 2017-08-03

Locations

1 site across 1 country: United States